PARALLEL DOPPLER ASSESSMENT OF YOLK-SAC AND INTERVILLOUS CIRCULATION IN NORMAL-PREGNANCY AND MISSED ABORTION

Citation
A. Kurjak et S. Kupesic, PARALLEL DOPPLER ASSESSMENT OF YOLK-SAC AND INTERVILLOUS CIRCULATION IN NORMAL-PREGNANCY AND MISSED ABORTION, Placenta (Eastbourne), 19(8), 1998, pp. 619-623
Citations number
15
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Developmental Biology","Obsetric & Gynecology","Reproductive Biology
Journal title
ISSN journal
0143-4004
Volume
19
Issue
8
Year of publication
1998
Pages
619 - 623
Database
ISI
SICI code
0143-4004(1998)19:8<619:PDAOYA>2.0.ZU;2-K
Abstract
This study assessed yolk sac morphology and vascularity and intervillo us blood flow in normal early pregnancy and missed abortion. Transvagi nal colour and pulsed Doppler were used in a prospective analysis of 8 7 normal pregnancies and 48 missed abortions between 6 and 12 weeks ge station. The Kruskal-Wallis rank test was used to calculate the differ ence in yolk sac diameter and vascularity visualization rate between g estational weeks. Repeated measures analysis of variance was used for comparison of the intervillous circulation between groups. The growth of the yell; sac was considered statistically significant between gest ational weeks 6 and 9, being most prominent between 9 and 10 weeks of gestation. Vascularity of the yolk sac, characterized by low velocity and absence of diastolic flow, was demonstrated in 67 per cent of norm al pregnancies. Yolk sac blood flow was detected in 19 per cent of the patients with missed abortion. Doppler analysis of the intervillous c irculation demonstrated decreased peak velocity of the continuous flow in patients with missed abortion for gestational weeks 11 and 12. It is concluded that progressive decrease of yolk sac vascularity coincid es with visualization of more prominent colour-coded areas within the intervillous space. In patients with missed abortion, such changes do not occur. (C) 1998 W. B. Saunders Company Ltd.