CONVENIENT ENANTIOSELECTIVE PREPARATION OF SALSOLINOL-1-CARBOXYLIC ACID

Citation
M. Kawai et al., CONVENIENT ENANTIOSELECTIVE PREPARATION OF SALSOLINOL-1-CARBOXYLIC ACID, Tetrahedron : asymmetry, 8(9), 1997, pp. 1487-1490
Citations number
8
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
ISSN journal
0957-4166
Volume
8
Issue
9
Year of publication
1997
Pages
1487 - 1490
Database
ISI
SICI code
0957-4166(1997)8:9<1487:CEPOSA>2.0.ZU;2-M
Abstract
Pictet-Spengler condensation of dopamine with (+)-menthyl pyruvate aff orded a diastereomeric mixture of menthyl salsolinol-1-carboxylate, fr om which pure diastereomer was isolated by repeated recrystallizations in ca. 20% yield. Acid hydrolysis of the menthyl ester furnished (-)- (R)-salsolinol-1-carboxylic acid in good yield. (C) 1997 Elsevier Scie nce Ltd.