THE LEADER SEQUENCE OF THE ESCHERICHIA-COLI LYSC GENE IS INVOLVED IN THE REGULATION OF LYSC SYNTHESIS

Citation
Jc. Patte et al., THE LEADER SEQUENCE OF THE ESCHERICHIA-COLI LYSC GENE IS INVOLVED IN THE REGULATION OF LYSC SYNTHESIS, FEMS microbiology letters, 169(1), 1998, pp. 165-170
Citations number
20
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Microbiology
Journal title
ISSN journal
0378-1097
Volume
169
Issue
1
Year of publication
1998
Pages
165 - 170
Database
ISI
SICI code
0378-1097(1998)169:1<165:TLSOTE>2.0.ZU;2-B
Abstract
In Escherichia coli and Bacillus subtilis, long leader sequences are f ound upstream of the lysC coding sequences which encode lysine-sensiti ve aspartokinase. Highly conserved regions exist between these sequenc es. Mutations leading to constitutive expression of the E. coli lysC g ene have been localised within these conserved regions, indicating tha t they participate in the lysine-mediated repression mechanism of lysC expression. (C) 1998 Federation of European Microbiological Societies . Published by Elsevier Science B.V. All rights reserved.