CELL-MEMBRANE EFFECTS OF SOME COMMON BIOCIDES

Citation
Isi. Aladham et al., CELL-MEMBRANE EFFECTS OF SOME COMMON BIOCIDES, Journal of industrial microbiology & biotechnology, 21(1-2), 1998, pp. 6-10
Citations number
29
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Biothechnology & Applied Migrobiology
Volume
21
Issue
1-2
Year of publication
1998
Pages
6 - 10
Database
ISI
SICI code
Abstract
Many antimicrobial compounds exhibit bacterial cell membrane activity as either potassium ion leakage and/or leakage of material that absorb s at 260 nm from the cell. In this experiment a potassium ion selectiv e electrode and spectophotometric observation of 260-nm leakage were u sed in order to examine cell membrane effects in a selection of common biocides upon both Escherichia coli NCIMB 10000 and Pseudomonas aerug inosa NCIMB 10548. The observation of potassium ion leakage for pyrith ione biocides yielded results which were initially difficult to interp ret, but are thought to suggest a species-dependent combination of pot assium ion leakage from affected membranes and chelation of those leak ed ions in the bathing suspension. Such a result is not, however, supp orted by the 260-nm material leakage results, which indicate very simi lar levels of membrane active effects for both species of bacteria.