EXPRESSION OF THE HOMEOBOX GENE GBX2 DURING CHICKEN DEVELOPMENT

Authors
Citation
K. Niss et A. Leutz, EXPRESSION OF THE HOMEOBOX GENE GBX2 DURING CHICKEN DEVELOPMENT, Mechanisms of development, 76(1-2), 1998, pp. 151-155
Citations number
11
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Developmental Biology
Journal title
ISSN journal
0925-4773
Volume
76
Issue
1-2
Year of publication
1998
Pages
151 - 155
Database
ISI
SICI code
0925-4773(1998)76:1-2<151:EOTHGG>2.0.ZU;2-D
Abstract
We have examined the expression pattern of the GBX2 gene during chicke n embryogenesis. First transcripts are found in the epiblast of a HH s t. 3+ embryo. With the onset of neurogenesis, transcripts mark the pos terior neuroectoderm. Later on, expression is detectable in the isthmi c region, the hindbrain and the neural tube. We show that GBX2 transcr ipts, as well as the protein, mark the presumptive hindbrain region. A fter establishment of the brain vesicles GBX2 transcripts were also de tected in distinct domains of the diencephalon. In addition to neural sites of expression, GBX2 was found in several domains including the o tic vesicle, the semitic mesoderm, the lateral foregut endoderm, the v entral limb bud ectoderm and in the feather buds. (C) 1998 Elsevier Sc ience Ireland Ltd. All rights reserved.