Background: In the field of gastrointestinal disease, productivity cos
ts are highly relevant because work loss is substantial in dyspeptic p
atients. Productivity costs are normally calculated by multiplying day
s absent valued by gross earnings. This, however, might lead to an ove
restimation, Aim: To use a conservative approach to calculating produc
tivity costs, taking absence compensating mechanisms into account, Met
hods: Patients who visited their general practitioner for the first ti
me with dyspeptic complaints and patients who were known to have persi
stent dyspeptic complaints were enrolled in two studies. In total, 136
patients completed a questionnaire about their employment situation,
absence from work and absence compensating mechanisms. Results: Sixty-
six of the respondents had a paid job, of which 25 (38%) reported abse
nce from work during the previous 4 weeks (average 3.0 days, 1.9 days
related to dyspeptic complaints). More than 50% of the employed respon
dents answered that absence could be compensated for by colleagues, an
d only in 8% of the cases was absence compensated for by overtime. Usi
ng our conservative approach, only one-quarter of the productivity cos
ts remained, compared to the current approach of valuing each day abse
nt as a loss of productivity, Conclusions: We suggest using both the c
urrent and the conservative approaches, analogous to the principles of
sensitivity analysis, to avoid overestimation of productivity costs.