ASYMMETRIC ACTIVATION OF CHIRAL BINOL-ZIRCONIUM CATALYSTS - EFFECT OFA PRODUCT-LIKE ACTIVATOR

Citation
T. Volk et al., ASYMMETRIC ACTIVATION OF CHIRAL BINOL-ZIRCONIUM CATALYSTS - EFFECT OFA PRODUCT-LIKE ACTIVATOR, Chirality, 10(7), 1998, pp. 717-721
Citations number
25
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry Medicinal","Chemistry Analytical","Chemistry Inorganic & Nuclear","Pharmacology & Pharmacy
Journal title
ISSN journal
0899-0042
Volume
10
Issue
7
Year of publication
1998
Pages
717 - 721
Database
ISI
SICI code
0899-0042(1998)10:7<717:AAOCBC>2.0.ZU;2-F
Abstract
The asymmetric activation of binaphthol (BINOL)-zirconium catalysts is described on the enantioselective allylation of benzaldehyde with all yltin reagents. This model reaction has been used with the intention o f establishing a protocol for a zirconium-based catalyst system, to be followed by structural studies. Initial results are reported that cha racterise a number of interesting features, namely the influence of an induction period and a high level of asymmetric activation obtained a fter addition of a product-like activator. (C) 1998 Wiley-Liss, Inc.