C. Andre et al., FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE AND TRANSKETOLASE - COMPLEMENTARY TOOLS FOR THE DE-NOVO SYNTHESES OF MONOSACCHARIDES AND ANALOGS, Journal of molecular catalysis. B, Enzymatic, 5(1-4), 1998, pp. 113-118
This paper reports a new synthesis of bromoacetol phosphate and dihydr
oxyacetone phosphate for use in fructose-1,6-bisphosphate aldolase (FB
-aldolase) catalyzed syntheses. Then the activities of FB-aldolase and
transketolase towards polyhydroxybutanal analogues of erythrose and e
rythrose-4-phosphate were studied. These activities were high enough t
o allow the syntheses of rare heptulose-1 -phosphates of the D and L s
eries. (C) 1998 Elsevier Science B.V. All rights reserved.