ENANTIOSELECTIVE SYNTHESIS OF 2-METHYL-2-(2-NITROETHENYL)-1-BENZOCYCLONES

Authors
Citation
Dx. Liu et R. Wang, ENANTIOSELECTIVE SYNTHESIS OF 2-METHYL-2-(2-NITROETHENYL)-1-BENZOCYCLONES, Gaodeng xuexiao huaxue xuebao, 19(9), 1998, pp. 1443-1445
Citations number
8
Language
CHINESE
art.tipo
Article
Categorie Soggetti
Chemistry
ISSN journal
0251-0790
Volume
19
Issue
9
Year of publication
1998
Pages
1443 - 1445
Database
ISI
SICI code
0251-0790(1998)19:9<1443:ESO2>2.0.ZU;2-M
Abstract
Optical active 2-methyl-2-(2-nitroethenyl)-1-tetralone and 2-methyl-2- (2-nitroethenyl)-1-indanone were synthesized via enantioselective addi tion-elimination reaction between nitroenamine (4) and the enolate of 2-methyl-1-benzocyclone (2). The chromatographic separation yield is 1 7%-73%, The E configuration of the olefinic bond and the enantiomer ex cess (8%-60%) of products were determined by 400 MHz H-1 NMR.