Dx. Liu et R. Wang, ENANTIOSELECTIVE SYNTHESIS OF 2-METHYL-2-(2-NITROETHENYL)-1-BENZOCYCLONES, Gaodeng xuexiao huaxue xuebao, 19(9), 1998, pp. 1443-1445
Optical active 2-methyl-2-(2-nitroethenyl)-1-tetralone and 2-methyl-2-
(2-nitroethenyl)-1-indanone were synthesized via enantioselective addi
tion-elimination reaction between nitroenamine (4) and the enolate of
2-methyl-1-benzocyclone (2). The chromatographic separation yield is 1
7%-73%, The E configuration of the olefinic bond and the enantiomer ex
cess (8%-60%) of products were determined by 400 MHz H-1 NMR.