F. Touchard et al., OPTICALLY-ACTIVE NITROGEN LIGANDS IN ASYMMETRIC CATALYSIS - EFFECT OFNITROGEN SUBSTITUTION ON THE ENANTIOSELECTIVE HYDRIDE TRANSFER REDUCTION OF ACETOPHENONE, Journal of organometallic chemistry, 567(1-2), 1998, pp. 133-136
Both theoretical calculations and experimental data have shown that on
ly one diamine ligand was necessary for the Rh catalytic enantioselect
ive hydride transfer reduction of acetophenone. A mechanism is propose
d. Different aza ligands were also tested in the same reaction, using
rhodium, ruthenium and iridium precursors. The structure-activity-sele
ctivity relationship of the aza ligands is discussed. (C) 1998 Elsevie
r Science S.A. All rights reserved.