REVIEW ARTICLE - THE DIAGNOSIS AND TREATMENT OF HEMATINIC DEFICIENCY IN GASTROINTESTINAL-DISEASE

Authors
Citation
R. Pawson et A. Mehta, REVIEW ARTICLE - THE DIAGNOSIS AND TREATMENT OF HEMATINIC DEFICIENCY IN GASTROINTESTINAL-DISEASE, Alimentary pharmacology & therapeutics, 12(8), 1998, pp. 687-698
Citations number
68
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Pharmacology & Pharmacy","Gastroenterology & Hepatology
ISSN journal
0269-2813
Volume
12
Issue
8
Year of publication
1998
Pages
687 - 698
Database
ISI
SICI code
0269-2813(1998)12:8<687:RA-TDA>2.0.ZU;2-5
Abstract
Deficiency of any of the vitamins and minerals essential for normal er ythropoiesis (haematinics), including iron, copper, cobalt, vitamins A , B-12, B-6, C, E, folic acid, riboflavin and nicotinic acid, may be a ssociated with defective erythropoiesis and anaemia. Iron, vitamin B-1 2 and folate are the haematinics for which deficiency states manifest most often clinically and are the focus of this review. The normal abs orption of these haematinics and gastrointestinal causes of their defi ciency are described. Investigations, including the use of homocystein e metabolite levels and new techniques such as serum transferrin recep tor assays, and treatment of haematinic deficiency are discussed in de tail.