A MODULAR APPROACH TO POTENTIAL SYNTHETIC RECEPTORS WITH LARGE SURFACES BASED ON CROWN[N]CAVITANDS

Citation
I. Higler et al., A MODULAR APPROACH TO POTENTIAL SYNTHETIC RECEPTORS WITH LARGE SURFACES BASED ON CROWN[N]CAVITANDS, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, (8), 1998, pp. 1597-1607
Citations number
29
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
1434-193X
Issue
8
Year of publication
1998
Pages
1597 - 1607
Database
ISI
SICI code
1434-193X(1998):8<1597:AMATPS>2.0.ZU;2-#
Abstract
Crown[n]cavitands were synthesized by alkylation of tetrahydroxycavita nds with polyethyleneglycol ditosylates. The bridging of two hydroxy g roups at adjacent aromatic rings by a pentaethyleneglycol unit is favo red over the bridging of two hydroxy groups at opposite aromatic rings . The presence of a sodium base enhances the formation of the 1,2-crow n[n]cavitand and improves the yield. The combination of 1,2-crown[6]ca vitands with calix[4]arenes or resorcin[4]arenes resulted in potential receptor molecules with large hydrophobic surfaces.