VARIATION IN TASTE OF TOPICAL LIGNOCAINE ANESTHESIA FOR GASTROSCOPY

Citation
Ma. Asante et Tc. Northfield, VARIATION IN TASTE OF TOPICAL LIGNOCAINE ANESTHESIA FOR GASTROSCOPY, Alimentary pharmacology & therapeutics, 12(7), 1998, pp. 685-686
Citations number
7
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Pharmacology & Pharmacy","Gastroenterology & Hepatology
ISSN journal
0269-2813
Volume
12
Issue
7
Year of publication
1998
Pages
685 - 686
Database
ISI
SICI code
0269-2813(1998)12:7<685:VITOTL>2.0.ZU;2-R
Abstract
Aim: To study the distribution and determinants of taste variation for lignocaine spray (Xylocaine; Astra Pharmaceuticals, King's Langley, U K). Methods: Sixty-nine patients (male:female 49:20, mean age 48.5 yea rs) attending for open access upper gastrointestinal endoscopy were st udied. Taste perceived after applying 4 doses (40 mg) of lignocaine sp ray to the ore-pharynx was recorded prior to endoscopy. Results: 37/69 (54%, 95% CI: 41-66%) perceived the taste of the lignocaine spray as bitter, whilst 24/69 (35%, 95% CI: 24-47%) and 6/69 (9%, 95% CI: 3-18% ) perceived the taste as either fruity/sweet or tasteless. The variati on in taste did not correlate with either demographic features or H. p ylori infection, but duodenal ulceration was slightly more common amon gst bitter tasters. Conclusion: The taste of lignocaine is not uniform , but the basis of this variability is uncertain.