CHIRAL SYNTHESIS OF TRI-O-METHYLIMBRICATINE, AN ETHERIFIED DERIVATIVEOF THE STARFISH ALKALOID IMBRICATINE

Citation
M. Ohba et al., CHIRAL SYNTHESIS OF TRI-O-METHYLIMBRICATINE, AN ETHERIFIED DERIVATIVEOF THE STARFISH ALKALOID IMBRICATINE, Tetrahedron letters, 39(33), 1998, pp. 5999-6002
Citations number
14
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
0040-4039
Volume
39
Issue
33
Year of publication
1998
Pages
5999 - 6002
Database
ISI
SICI code
0040-4039(1998)39:33<5999:CSOTAE>2.0.ZU;2-Q
Abstract
A chiral synthesis of tri-O-methylimbricatine (2), the tri-O-methyl de rivative of the unique benzyltetrahydroisoquinoline alkaloid imbricati ne (1) isolated from the starfish Dermasterias imbricata, has been acc omplished. As a result of the synthesis, the correctness of the struct ure and absolute stereochemistry proposed for imbricatine has been une quivocally confirmed. (C) 1998 Elsevier Science Ltd. All rights reserv ed.