GASTRIC VASCULAR NETWORK IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS

Citation
A. Chiba et al., GASTRIC VASCULAR NETWORK IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS, Research communications in molecular pathology and pharmacology, 100(1), 1998, pp. 65-76
Citations number
32
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Pharmacology & Pharmacy",Pathology,Biology
ISSN journal
1078-0297
Volume
100
Issue
1
Year of publication
1998
Pages
65 - 76
Database
ISI
SICI code
1078-0297(1998)100:1<65:GVNISS>2.0.ZU;2-C
Abstract
The gastric vascular architecture in stroke-prone spontaneously hypert ensive rats (SHRSP) was studied three-dimensionally by vascular castin g; controls were Wistar Kyoto rats (WKY). The vascular network of the gastric mucosa of WKY showed a cylindrical shape with regular morpholo gy (honeycomb-like capillary network) along the vascular course. In co ntrast, in SHRSP, an irregular vascular network was formed, and arteri oles in the gastric mucosa and serous membrane were difficult to detec t. Aneurysms were also detected in some capillaries in SHRSP. We concl uded that the development of hypertension may have caused the irregula r capillary networks in the rat stomach.