ALCOHOL INTAKE AND RISK OF CANCERS OF THE COLON AND RECTUM

Citation
A. Tavani et al., ALCOHOL INTAKE AND RISK OF CANCERS OF THE COLON AND RECTUM, Nutrition and cancer, 30(3), 1998, pp. 213-219
Citations number
29
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Nutrition & Dietetics",Oncology
Journal title
ISSN journal
0163-5581
Volume
30
Issue
3
Year of publication
1998
Pages
213 - 219
Database
ISI
SICI code
0163-5581(1998)30:3<213:AIAROC>2.0.ZU;2-2
Abstract
The relationship between alcohol drinking (mainly wine) and risk of co lon and rectal cancer was considered in a case-control study conducted between 1991 and 1996 in six Italian centers. Cases were 1,225 patien ts <75 years of age with histologically confirmed cancer of the colon and 728 patients with cancer of the rectum; controls were 4,154 patien ts admitted to hospital for a wide spectrum of acute, nonneoplastic di seases. Compared with never drinkers, the odds ratios (OR) for current drinkers in the higher quintile of total alcohol intake (>51.82 g eth anol/day) were 1.01 for colon cancer and 0.90 for rectal cancer, and t hose for ex-drinkers were 1.20 and 1.07, respectively. The OR for wine drinkers in the highest quartile of intake were 1.07 for colon cancer and 0.97 for rectal cancer. No association was found with duration of the habit, time since starting. or age at starting. Among ex-drinkers , no association appeared with time since stopping. No significant het erogeneity was found across strata of age at diagnosis, sex, education , smoking status, physical activity family history of colorectal cance r, beta-carotene, vitamin C, coffee, total fiber and folate intake, an d number of meals per day. No significant association appeared for var ious intestinal subsites.