THE SAPHO SYNDROME - DEFINING THE RADIOLOGIC SPECTRUM OF DISEASES COMPRISING THE SYNDROME

Citation
H. Sugimoto et al., THE SAPHO SYNDROME - DEFINING THE RADIOLOGIC SPECTRUM OF DISEASES COMPRISING THE SYNDROME, European radiology, 8(5), 1998, pp. 800-806
Citations number
30
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
Journal title
ISSN journal
0938-7994
Volume
8
Issue
5
Year of publication
1998
Pages
800 - 806
Database
ISI
SICI code
0938-7994(1998)8:5<800:TSS-DT>2.0.ZU;2-D
Abstract
The objective of our study was to clarify the radiologic spectrum of d isease entities belonging to the SAPHO syndrome (SAPHO being an acrony m for synovitis, acne, pustulosis, hyperostosis, and osteitis). A retr ospective analysis of radiologic data was undertaken to determine the relationship of the osteoarthritic changes seen in palmoplantar pustul osis (PPP, n = 179), acne (n = 3), psoriasis vulgaris (PsV, n = 355), generalized pustular psoriasis (GPP; n = 25), and chronic recurrent mu ltifocal osteomyelitis (CRMO, n = 4). Osseous changes of PPP, acne, an d CRMO overlap each other; 7 PPP, 2 acne, and 3 CRMO patients manifest ed stenocostoclavicular hyperostosis as well as hyperostosis of the sp ine, pelvis, and/or femur. These findings were not seen in either PsV or GPP patients. Thirteen PsV and 4 GPP patients had peripheral arthri tis and/or symmetrical sacroiliitis, which were not observed in the PP P, acne, and CRMO patients. The PPP, acne, and CRMO patients may be gr ouped as belonging to the single disease entity, namely SAPHO syndrome . Our findings do not support the inclusion of PsV and GPP in the spec trum of this syndrome.