INCREASED CONVERSION RATIO OF TRYPTOPHAN TO NIACIN IN SEVERE FOOD RESTRICTION

Citation
K. Shibata et al., INCREASED CONVERSION RATIO OF TRYPTOPHAN TO NIACIN IN SEVERE FOOD RESTRICTION, Bioscience, biotechnology, and biochemistry, 62(3), 1998, pp. 580-583
Citations number
24
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Biology,Agriculture,"Biothechnology & Applied Migrobiology","Food Science & Tenology
ISSN journal
0916-8451
Volume
62
Issue
3
Year of publication
1998
Pages
580 - 583
Database
ISI
SICI code
0916-8451(1998)62:3<580:ICROTT>2.0.ZU;2-0
Abstract
The effect of food restriction on the conversion ratio of tryptophan t o niacin was investigated, because it is known that the conversion rat io is influenced by nutritional factors. A 20% casein diet was fed to rats ad libitum (control), 1/2 the food of the control. 1/4 the food o f the control, or starved for 9 days, and urine samples were collected to measure the urinary excretion of such tryptophan metabolites as ky nurenic acid, xanthurenic acid, and nicotinamide, The conversion ratio in the 1/2, 1/4, or starving group increased at day I of the experime nt, but returned to the original value from day 2, only in the starvin g group did the conversion ratio extremely increase from day 6 to day 9, being about 5-times higher than that of the original value on day 9 . The possible mechanism by which the conversion ratio increased durin g food restriction is discussed.