HEIGHT AND BREAST-CANCER RISK

Citation
A. Tavani et al., HEIGHT AND BREAST-CANCER RISK, European journal of cancer, 34(4), 1998, pp. 543-547
Citations number
48
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Oncology
Journal title
ISSN journal
0959-8049
Volume
34
Issue
4
Year of publication
1998
Pages
543 - 547
Database
ISI
SICI code
0959-8049(1998)34:4<543:>2.0.ZU;2-B
Abstract
The relationship between adult height and breast cancer risk was consi dered, combining data from two case-control studies, one conducted bet ween 1983 and 1991 in northern Italy and the other between 1991 and 19 94 in six Italian centres. Cases were 5984 women, below the age of 75 years, with histologically confirmed breast cancer, and controls were 5504 women admitted to hospital for a wide spectrum of acute, non-neop lastic, non-hormone-related diseases. No relationship was observed bet ween height and the risk of breast cancer, with a multivariate odds ra tio (OR) of 0.96 (95% confidence intervals (CI) 0.85-1.08) for the tal lest women (height greater than or equal to 166 cm) compared with the shortest (height < 156 cm). No significant heterogeneity was found acr oss strata of age at diagnosis, education, body mass index, body weigh t, alcohol intake, age at menarche and menopause, parity, age at first birth, ever use of oral contraceptives and hormone replacement therap y, history of benign breast disease and family history of breast cance r. Thus, this study indicates that adult height is not appreciably rel ated to breast cancer risk in this Italian population. (C) 1998 Elsevi er Science Ltd. All rights reserved.