STEREOCHEMISTRY OF THE REDUCTION OF 24-ETHYLDESMOSTEROL TO SITOSTEROLIN TISSUE-CULTURES OF ORYZA-SATIVA

Citation
Y. Fujimoto et al., STEREOCHEMISTRY OF THE REDUCTION OF 24-ETHYLDESMOSTEROL TO SITOSTEROLIN TISSUE-CULTURES OF ORYZA-SATIVA, Bioorganic & medicinal chemistry letters, 8(3), 1998, pp. 205-208
Citations number
15
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
ISSN journal
0960-894X
Volume
8
Issue
3
Year of publication
1998
Pages
205 - 208
Database
ISI
SICI code
0960-894X(1998)8:3<205:SOTRO2>2.0.ZU;2-4
Abstract
Feeding of [26-C-13]- and [27-C-13]-24-ethyldesmosterols to cultured c ells of Oryza sativa followed by C-13-NMR analysis of the biosynthesiz ed sitosterol revealed that the reduction of 24(25)-double bond procee ds with an anti-addition of hydrogen atoms, thus the E-methyl group of the olefinic precursor becomes the pro-S-methyl on C-25 of sitosterol . (C) 1998 Elsevier Science Ltd. All rights reserved.