Y. Fujimoto et al., STEREOCHEMISTRY OF THE REDUCTION OF 24-ETHYLDESMOSTEROL TO SITOSTEROLIN TISSUE-CULTURES OF ORYZA-SATIVA, Bioorganic & medicinal chemistry letters, 8(3), 1998, pp. 205-208
Feeding of [26-C-13]- and [27-C-13]-24-ethyldesmosterols to cultured c
ells of Oryza sativa followed by C-13-NMR analysis of the biosynthesiz
ed sitosterol revealed that the reduction of 24(25)-double bond procee
ds with an anti-addition of hydrogen atoms, thus the E-methyl group of
the olefinic precursor becomes the pro-S-methyl on C-25 of sitosterol
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