GENETIC-ANALYSIS OF THE ACTIN CYTOSKELETON IN THE DROSOPHILA OVARY

Citation
Dn. Robinson et L. Cooley, GENETIC-ANALYSIS OF THE ACTIN CYTOSKELETON IN THE DROSOPHILA OVARY, Annual review of cell and developmental biology, 13, 1997, pp. 147-170
Citations number
110
Language
INGLESE
art.tipo
Review
ISSN journal
1081-0706
Volume
13
Year of publication
1997
Pages
147 - 170
Database
ISI
SICI code
1081-0706(1997)13:<147:GOTACI>2.0.ZU;2-5
Abstract
The Drosophila ovary provides a favorable model system in which to stu dy cellular morphogenesis. The development of a mature egg involves a syncytium of 16 germline cells and over 1000 somatically derived folli cle cells. Intercellular transport, stable intercellular bridges, cell migrations, cell shape changes, and specific subcellular localization of many embryonic patterning determinants contribute to egg developme nt and require a dynamic cytoskeleton. We discuss many of the recent g enetic and cell biological studies that have led to insights into how the actin cytoskeleton is assembled and regulated during the morphogen esis of the Drosophila egg.