LEFT-RIGHT ASYMMETRY IN ANIMAL DEVELOPMENT

Authors
Citation
Wb. Wood, LEFT-RIGHT ASYMMETRY IN ANIMAL DEVELOPMENT, Annual review of cell and developmental biology, 13, 1997, pp. 53-82
Citations number
91
Language
INGLESE
art.tipo
Article
ISSN journal
1081-0706
Volume
13
Year of publication
1997
Pages
53 - 82
Database
ISI
SICI code
1081-0706(1997)13:<53:LAIAD>2.0.ZU;2-9
Abstract
Most animal species exhibit left-right asymmetry in their body plans a nd show a strong bias for one handedness over the other. The mechanism of handedness choice, recognized as an intriguing problem over a cent ury ago, is still a mystery. However, from recent advances in understa nding when and how asymmetry arises in both invertebrates and vertebra tes, developmental pathways for establishment and maintenance of left- right differences are beginning to take shape, and speculations can be made on the initial choice mechanism.