SYNTHESIS OF OLIGOPEPTIDE AND PEPTIDOMIMETIC LIBRARIES

Citation
Vj. Hruby et al., SYNTHESIS OF OLIGOPEPTIDE AND PEPTIDOMIMETIC LIBRARIES, CURRENT OPINION IN CHEMICAL BIOLOGY, 1(1), 1997, pp. 114-119
Citations number
60
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Biology,Biophysics
ISSN journal
1367-5931
Volume
1
Issue
1
Year of publication
1997
Pages
114 - 119
Database
ISI
SICI code
1367-5931(1997)1:1<114:SOOAPL>2.0.ZU;2-X
Abstract
The elaboration of peptide libraries prepared by either chemical or bi ological methods in a format useful for discovery of peptides with spe cific biological activities was first introduced in the 1980s. A virtu al explosion of activity in this area has occurred recently, and the b asic approaches have been applied to a wide variety of chemistries and for all manner of biological, chemical and physical targets. Recent a dvances include new synthetic methodologies, new analytical methods, n ew design methods and new assay procedures.