IMMUNOTHERAPY BEFORE AND DURING PREGNANCY IMPROVES PREGNANCY OUTCOME IN WOMEN WHO SUFFER FROM RECURRENT ABORTION AND DID NOT BENEFIT FROM IMMUNOTHERAPY BEFORE PREGNANCY

Citation
M. Maejima et al., IMMUNOTHERAPY BEFORE AND DURING PREGNANCY IMPROVES PREGNANCY OUTCOME IN WOMEN WHO SUFFER FROM RECURRENT ABORTION AND DID NOT BENEFIT FROM IMMUNOTHERAPY BEFORE PREGNANCY, AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 39(1), 1998, pp. 12-15
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Reproductive Biology",Immunology
ISSN journal
1046-7408
Volume
39
Issue
1
Year of publication
1998
Pages
12 - 15
Database
ISI
SICI code
1046-7408(1998)39:1<12:IBADPI>2.0.ZU;2-7
Abstract
PROBLEM: The appropriate modality of immunotherapy with the husband's mononuclear cells in women with a history of recurrent abortion who ab orted despite the immunotherapy performed before pregnancy was explore d. METHOD OF STUDY: Nineteen patients who had suffered from recurrent abortion who had received the immunotherapy only before pregnancy and had aborted were treated with further immunotherapy performed either o nly before pregnancy or twice: before and during pregnancy. RESULTS: I n 9 out of the 19 women who received further immunotherapy before preg nancy, 2 had healthy babies and 7 aborted again. In the remaining 10 p atients who received further immunotherapy twice, before and during pr egnancy, 8 had healthy babies and 2 aborted again. CONCLUSION: Our res ults indicate that immunotherapy performed before and during pregnancy produces a better outcome compared with that performed only before pr egnancy, especially in patients who showed no benefit from the immunot herapy performed only before pregnancy.