Euplexides A-E: Novel farnesylhydroquinone glycosides from the gorgonian Euplexaura anastomosans

Citation
J. Shin et al., Euplexides A-E: Novel farnesylhydroquinone glycosides from the gorgonian Euplexaura anastomosans, J ORG CHEM, 64(6), 1999, pp. 1853-1858
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
0022-3263 → ACNP
Volume
64
Issue
6
Year of publication
1999
Pages
1853 - 1858
Database
ISI
SICI code
0022-3263(19990319)64:6<1853:EANFGF>2.0.ZU;2-Q
Abstract
Euplexides A-E (1-5), novel farnesylhydroquinone glycosides of the moritosi de class, have been isolated from the gorgonian Euplexaura anastomosans. Th e structures of these compounds have been elucidated by combined chemical a nd spectral methods. The absolute stereochemistry has been determined by th e modified Mosher's method and an acidic hydrolysis followed by GC analysis . These compounds exhibited moderate cytotoxicity and antioxidizing activit y as well as inhibitory activity against PLA(2).