Varicella syndrome (VS) specific malformations were sonographically seen at
22 weeks and 3 days of gestation. Fetal infection was demonstrated by dete
ction of varicella-zoster virus (VZV) DNA in fetal blood and amniotic fluid
by polymerase chain reaction (PCR). Following therapeutic abortion, fetal
infection was confirmed by detection of VZV DNA in several fetal tissues an
d placenta, and by histopathological findings like miliary calcified necros
es in fetal organs. Copyright (C) 1999 John Wiley & Sons, Ltd.