Lower extremity occlusive disease: Diagnostic imaging with a combination of cardiac-gated 2D phase-contrast and cardiac-gated 2D time-of-flight MRA

Citation
Jc. Steffens et al., Lower extremity occlusive disease: Diagnostic imaging with a combination of cardiac-gated 2D phase-contrast and cardiac-gated 2D time-of-flight MRA, J COMPUT AS, 23(1), 1999, pp. 7-12
Citations number
26
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Medical Research Diagnosis & Treatment
Journal title
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY
ISSN journal
0363-8715 → ACNP
Volume
23
Issue
1
Year of publication
1999
Pages
7 - 12
Database
ISI
SICI code
0363-8715(199901/02)23:1<7:LEODDI>2.0.ZU;2-U
Abstract
Purpose: The goal of this work was to test the ability of a combination of 2D phase-contrast MR angiography (2D-PC-MRA) and triggered 2D time-of-fligh t MRA (2D-TOF-MRA) in comparison to intraarterial digital subtraction angio graphy (DSA) to correctly diagnose the location and shape of occlusive lesi ons in the iliac and femoral arteries and to determine whether 2D-TOF-MRA i s helpful to clarify questionable lesions demonstrated by 2D-PC-MRA. Methods: In 50 patients with claudication, 2D-PC-MRA was performed in three consecutive coronal positions from the aortic bifurcation to below the tri furcation. Axial 2D-TOF-MRA was performed additionally at the site of detec ted lesions of >50% and lesions in doubt to obtain more precise information about the stenosis. Lesions were classified as follows: low grade occlusio n, <50%; high grade occlusion, >50%. MRA was performed within 24 h of a DSA examination. Results: In all patients, the arterial tree from the aortic bifurcation to the trifurcation could be visualized. One hundred twelve lesions were detec ted by MRA. Sensitivity was 96% and specificity was 92%. Sixty-two lesions were classified as high grade occlusion and reevaluated. In this category, sensitivity was 100% and specificity was 96%. Conclusion: The combination of 2D-PC-MRA with triggered 2D-TOF-MRA detects stenotic lesions in the lower extremity arterial system with high sensitivi ty and specificity.