Infection rate of Leptospira interrogans in the field rodent, Apodemus agrarius, in Korea

Citation
Mk. Cho et al., Infection rate of Leptospira interrogans in the field rodent, Apodemus agrarius, in Korea, EPIDEM INFE, 121(3), 1998, pp. 685-690
Citations number
20
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Medical Research General Topics
Journal title
EPIDEMIOLOGY AND INFECTION
ISSN journal
0950-2688 → ACNP
Volume
121
Issue
3
Year of publication
1998
Pages
685 - 690
Database
ISI
SICI code
0950-2688(199812)121:3<685:IROLII>2.0.ZU;2-5
Abstract
Leptospirosis has significantly decreased in Korea since 1988, following th e leptospiral vaccination programme initiated in 1988. Whether this wholly explains the decreased incidence is uncertain. As an initial step to answer this question, infection rates of Leptospira interrogans in field rodents, Apodemis agrarius, were examined and compared with previous data. Two hundred and twenty-two A. agrarius were captured during October-Decembe r 1996. Spirochaetes were isolated from 22 (9.9 %) and leptospiral DNA was detected in an additional 6 rodents (12.6 %). Subsequent microscopic agglut ination tests (MAT) classified all these isolates as L. interrogans serogro up Icterohaemorrhagiae serovar lai. The above data did not significantly di ffer from previous surveys in 1984-7. There was no significant change of L. interrogans infection in field rodents following the introduction of the v accination programme in Korea, Further studies are needed to determine the role of human vaccination in reducing incidence.