Synthesis and characterization of long chain alkyl stationary phases on a silica hydride surface

Citation
Jj. Pesek et al., Synthesis and characterization of long chain alkyl stationary phases on a silica hydride surface, CHROMATOGR, 48(9-10), 1998, pp. 631-636
Citations number
16
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
CHROMATOGRAPHIA
ISSN journal
0009-5893 → ACNP
Volume
48
Issue
9-10
Year of publication
1998
Pages
631 - 636
Database
ISI
SICI code
0009-5893(199811)48:9-10<631:SACOLC>2.0.ZU;2-J
Abstract
C-22 and C-30 alkyl chains were attached to a silica hydride surface by a h ydrosilation reaction. In each case both moieties were successfully bonded by either metal complex catalysis or free radical initiation. Carbon analys is, DRIFT spectra and C-13 CP-MAS NMR spectra confirm the bonding of the ol efin to silica hydride. Conditions for maximum coverage were determined by a simplex procedure. Chromatographic evaluation of these long chain bonded phases was accomplished by separations of several types of mixtures: alkyl substituted benzenes, polycyclic aromatic hydrocarbons; carotenoids, tocoph erols; tricyclic antidepressants; and peptides. The C-30 column proved sign ificantly better for separating the carotenoid and antidepressant mixtures and somewhat better for the peptide sample.