Effect of ionizing radiation on the thermal oxidative stability of medicalpolymers

Citation
L. Woo et al., Effect of ionizing radiation on the thermal oxidative stability of medicalpolymers, THERMOC ACT, 324(1-2), 1998, pp. 179-185
Citations number
5
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
THERMOCHIMICA ACTA
ISSN journal
0040-6031 → ACNP
Volume
324
Issue
1-2
Year of publication
1998
Pages
179 - 185
Database
ISI
SICI code
0040-6031(199812)324:1-2<179:EOIROT>2.0.ZU;2-L
Abstract
In the medical-device industry, most products need to be sterilized prior t o use. Sterilization by ionizing radiation is fast becoming the preferred m ethod on account of its effectiveness and economy. However, energetic secon dary electrons released from the primary irradiation event can cause signif icant damage and degrade the polymer. We have undertaken a study on the the rmal oxidative stability of several medical polymers as measured by the oxi dative induction time (OIT) on radiation exposures. It was found that, in s elected cases with polyolefins, active antioxidants can be completely consu med during the sterilization process, leaving the polymer unprotected for t he required shelf life. In addition, comparison between gamma- and electron -beam irradiation sources revealed major differences on OIT reduction, prim arily due to the dose rate effect. (C) 1998 Elsevier Science B.V. All right s reserved.