TOFE human-B-cell-line-based adsorption-inhibition assay to detect HCV neutralizing antibodies

Citation
Mb. Valli et al., TOFE human-B-cell-line-based adsorption-inhibition assay to detect HCV neutralizing antibodies, RES VIROL, 149(5), 1998, pp. 331-333
Citations number
10
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Microbiology
Journal title
RESEARCH IN VIROLOGY
ISSN journal
0923-2516 → ACNP
Volume
149
Issue
5
Year of publication
1998
Pages
331 - 333
Database
ISI
SICI code
0923-2516(199809/10)149:5<331:THAATD>2.0.ZU;2-O
Abstract
We previously demonstrated that the human lymphoblastoid B cell line (LCL) TOFE, derived from normal human bone marrow, is permissive to HCV infection . In this report we developed an in vitro HCV adsorption-inhibition assay b ased on TOFE cells, to reveal the presence of neutralizing antibodies in se ra from acutely infected patients.