Prognosis of Japanese encephalitis: a multivariate analysis

Citation
Uk. Misra et al., Prognosis of Japanese encephalitis: a multivariate analysis, J NEUR SCI, 161(2), 1998, pp. 143-147
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Neurosciences & Behavoir
Journal title
JOURNAL OF THE NEUROLOGICAL SCIENCES
ISSN journal
0022-510X → ACNP
Volume
161
Issue
2
Year of publication
1998
Pages
143 - 147
Database
ISI
SICI code
0022-510X(199812)161:2<143:POJEAM>2.0.ZU;2-Z
Abstract
To evaluate the role of various clinical neurophysiological laboratory and radiological parameters in the prognosis of Japanese encephalitis (JE), 28 patients were prospectively evaluated. Their age ranged between two and 54 years, with eight of them being female and 11 children. The outcome was def ined, at the end of a six-month period, as being poor (bed-ridden), partial (partial dependence for activity for daily life) and complete recovery (in dependent for activities of daily life). A number of clinical (age, degree of coma, decerebration or decortication and reflex changes), laboratory (CS F cell and protein content, and haemagglutination inhibition titre in the s erum), neurophysiological (EEG, EMG, sensory and motor evoked potentials) a nd the extent of radiological changes were subjected to stepwise multivaria te logistic regression analysis. By the end of six months, four patients ha d died, seven had poor, ten partial and seven had complete recovery. The be st set of predictors of outcome included age, Glasgow coma scale and reflex changes. (C) 1998 Elsevier Science B.V. All rights reserved.