Prognostic value of treadmill exercise testing - A population-based study in Olmsted County, Minnesota

Citation
Vl. Roger et al., Prognostic value of treadmill exercise testing - A population-based study in Olmsted County, Minnesota, CIRCULATION, 98(25), 1998, pp. 2836-2841
Citations number
34
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
CIRCULATION
ISSN journal
0009-7322 → ACNP
Volume
98
Issue
25
Year of publication
1998
Pages
2836 - 2841
Database
ISI
SICI code
0009-7322(199812)98:25<2836:PVOTET>2.0.ZU;2-6
Abstract
Background-The prognostic value of treadmill exercise testing (TMET) has be en studied in selected populations. The generalizability of these data to d ifferent populations and to women is uncertain. Methods and Results-A retrospective, population-based cohort study of all p ersons (1452 men and 741 women) who underwent TMET in years 1987 to 1989 in Olmsted County, Minnesota, was undertaken. Individuals were followed up fo r all-cause mortality and cardiac events (cardiac deaths, nonfatal myocardi al infarction, or congestive heart failure). Sex-specific analyses were per formed to determine whether the predictors of outcome and the magnitude of the associations were similar in both sexes. In men, 77 deaths and 106 card iac events occurred during 8956 person-years of observation; in women, 46 d eaths and 54 cardiac events occurred during 4801 person-years of follow-up. Exercise-induced angina, ECG changes, and workload achieved on the TMET we re strongly associated with all-cause mortality and cardiac events in both sexes, and the strength of the association was similar. After adjustment, w orkload was the only TMET variable associated with outcome. A higher worklo ad was associated with a reduction in the risk of cardiac events and of all -cause mortality; the protective effect of exercise capacity was strong and was similar in both sexes. Conclusions-In this population-based cohort, exercise capacity was the TMET variable that exhibited the strongest association with all-cause mortality and cardiac events. This protective effect of exercise capacity was observ ed in both sexes.