Lipoblastoma presenting as a mesenteric mass in an infant

Citation
Y. Posey et al., Lipoblastoma presenting as a mesenteric mass in an infant, J PED H ONC, 20(6), 1998, pp. 580-582
Citations number
17
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Pediatrics
Journal title
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
ISSN journal
1077-4114 → ACNP
Volume
20
Issue
6
Year of publication
1998
Pages
580 - 582
Database
ISI
SICI code
1077-4114(199811/12)20:6<580:LPAAMM>2.0.ZU;2-R
Abstract
Purpose: This article describes an infant with a large abdominal mass and h ypertension Patient and Methods: A 5-month-old infant girl with diarrhea of 1 week's du ration and a large right-sided abdominal mass was brought far treatment. Co mputed tomography of the abdomen revealed a large, generally homogeneous, h ypodense mass, which compressed the right kidney, resulting in dilatation o f the right renal collecting system. At surgery, the mass was adherent ante riorly to the transverse colon and attached by a stalk to the mesentery nea r the origin of the right colic artery. Results: Examination of the mass showed an encapsulated lipoblastoma. Cytog enetic analysis revealed a 46,XX karyotype with a reciprocal translocation between chromosome 2 and chromosome 8 with breakpoints at q23 and q11.2, re spectively. Conclusion: Lipoblastoma is a rapidly growing but benign tumor, which can c ause severe medical problems by compressing major organs. Cytogenetic analy sis can reveal translocations involving chromosome 8 band q11.2, which appe ars to be a specific chromosome marker for lipoblastoma.