Primary malignant melanoma of the female urethra comprises 0.2% of all mela
nomas and has poor prognosis. In the period 1972-1992, 75 cases of primary
urethra carcinomas were treated at the Roswell Park Cancer Institute. Among
them, only an 80-year-old woman was diagnosed with primary malignant melan
oma. Despite conservative treatment, she lived for 7 years. We believe that
local surgical excision can be an option for treatment in selected patient
s as it retains quality of life.