DIET AND RISK OF LYMPHOID NEOPLASMS AND SOFT-TISSUE SARCOMAS

Citation
A. Tavani et al., DIET AND RISK OF LYMPHOID NEOPLASMS AND SOFT-TISSUE SARCOMAS, Nutrition and cancer, 27(3), 1997, pp. 256-260
Citations number
26
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Nutrition & Dietetics",Oncology
Journal title
ISSN journal
0163-5581
Volume
27
Issue
3
Year of publication
1997
Pages
256 - 260
Database
ISI
SICI code
0163-5581(1997)27:3<256:DAROLN>2.0.ZU;2-6
Abstract
The relationship between frequency of intake of selected indicator foo ds, lymphoid neoplasms, and soft tissue sarcomas was investigated in a n updated case-control study conducted in Northern Italy between 1983 and 1992 on 158 incident, histologically confirmed cases of Hodgkin's disease (HD), 429 cases of non-Hodgkin's lymphoma (NHL), 141 cases of multiple myelomas, 101 cases of soft tissue sarcomas, and 1,157 contro ls admitted to hospital for acute, nonneoplastic diseases unrelated to long-term modifications of diet. Compared with the lowest tertile, th e odds ratio (OR) for the highest tertile of milk intake was 1.8 for N HL and 1.9 for sarcomas, Liver intake was an indicator of the risk of HD (OR = 1.8), NHL (OR = 1.6), and myelomas (OR = 2.0), ham an indicat or of HD (OR = 1.7), and butter an indicator of myelomas (OR = 2.8). A high consumption of green vegetables was inversely related to myeloma s (OR = 0.4), and frequent use of whole-grain foods was inversely rela ted to NHL (OR = 0.4) and soft tissue sarcomas (OR = 0.2). No material association with meat was observed for any of the neoplasms considere d. Likewise, coffee and alcohol intakes were not associated with lymph oid neoplasms and soft tissue sarcomas. The OR for the highest tertile of intake of beta-carotene ranged between 0.5 and 0.7, whereas the OR for retinol ranged between 1.5 and 2.3. Although available data do no t point to any specific inference, this study suggests that certain as pects of diet are a correlate or an indicator of the risk of lymphoid neoplasms and soft tissue sarcomas.