A. Ohta et al., LOCALIZATION OF NITRIC-OXIDE SYNTHASE-IMMUNOREACTIVE NEURONS IN THE SOLITARY NUCLEUS AND VENTROLATERAL MEDULLA-OBLONGATA OF THE RAT - THEIRRELATION TO CATECHOLAMINERGIC NEURONS, Neuroscience letters, 158(1), 1993, pp. 33-35
The morphological relationship between nitric oxide (NO) and catechola
mines in the solitary nucleus (SOL) and ventrolateral medulla oblongat
a (VLM) was studied by a double immunostaining method with antibodies
against NO synthase (NOS), an NO-synthesizing enzyme, and tyrosine hyd
roxylase (TH), a catecholamine-synthesizing enzyme. Although NOS- and
TH-immunoreactive neurons were widely distributed in the SOL and VLM,
these immunoreactivities did not coexist in any single neurons. NOS-im
munoreactive neurons formed clusters in some restricted regions, i.e.
in the medial subnucleus of the SOL, where both NOS- and TH-immunoreac
tive neurons showed a complementary distribution. These findings sugge
st that NO-producing neurons constitute a subclass that is distinct fr
om that of catecholaminergic neurons.