ALCOHOL AND CANCER

Authors
Citation
Wj. Blot, ALCOHOL AND CANCER, Cancer research, 52(7), 1992, pp. 2119-2123
Citations number
52
Language
INGLESE
art.tipo
Article
Journal title
ISSN journal
0008-5472
Volume
52
Issue
7
Year of publication
1992
Supplement
S
Pages
2119 - 2123
Database
ISI
SICI code
0008-5472(1992)52:7<2119:AAC>2.0.ZU;2-6
Abstract
Although ethanol has generally not been found to induce cancer in expe rimental animals, the consumption of alcoholic beverages has been link ed to increased risks of several cancers in humans. Risks of oral, pha ryngeal, laryngeal, esophageal, and liver cancer are elevated among dr inkers, typically in proportion to the amount consumed. Evidence assoc iating colorectal and breast cancer with alcohol drinking is suggestiv e but awaits confirmation. All types of alcoholic beverages seem to be implicated, pointing to an etiological role for ethanol or its metabo lites. The mechanisms, however, by which alcohol induces cancer in hum ans are not clear. This review summarizes epidemiological studies of a lcohol and cancer, focusing primarily on characteristics of the associ ation that may provide clues to causal pathways.