PHENOTYPIC VARIATION IN HEREDITARY NONPOLYPOSIS COLON CANCER SYNDROME- ASSOCIATION WITH INFILTRATIVE FIBROMATOSIS (DESMOID TUMOR)

Citation
Er. Maher et al., PHENOTYPIC VARIATION IN HEREDITARY NONPOLYPOSIS COLON CANCER SYNDROME- ASSOCIATION WITH INFILTRATIVE FIBROMATOSIS (DESMOID TUMOR), Cancer, 69(8), 1992, pp. 2049-2051
Citations number
17
Language
INGLESE
art.tipo
Article
Journal title
CancerACNP
ISSN journal
0008-543X
Volume
69
Issue
8
Year of publication
1992
Pages
2049 - 2051
Database
ISI
SICI code
0008-543X(1992)69:8<2049:PVIHNC>2.0.ZU;2-9
Abstract
Familial infiltrative fibromatosis (desmoid tumor) is a recognized com plication of familial adenomatous polyposis (FAP) but has not been des cribed in families without colonic polyposis. The authors describe a u nique family in which a predisposition to infiltrative fibromatosis an d nonpolyposis colon cancer was inherited dominantly through four gene rations. This report expands the range of phenotypic variation describ ed for the hereditary non-polyposis colon cancer (HNPCC) syndrome and adds to the extracolonic complications that are common with FAP and HN PCC.