A SPIRO-INDOLE DERIVATIVE, C16H10CLFN2O2S

Citation
V. Sehgal et al., A SPIRO-INDOLE DERIVATIVE, C16H10CLFN2O2S, Acta crystallographica. Section C, Crystal structure communications, 50, 1994, pp. 1156-1159
Citations number
11
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Crystallography
ISSN journal
0108-2701
Volume
50
Year of publication
1994
Part
7
Pages
1156 - 1159
Database
ISI
SICI code
0108-2701(1994)50:<1156:ASDC>2.0.ZU;2-C
Abstract
The spiro-indole derivative, spiro[3H-indole-3,2'-thiazolidine]-2,4'(1 H)-dione, has been synthesized by the reaction of mercaptoacetic acid with 5-chloroimino-3-(4-fluoro-phenyl)-2H-indol-2-one. The latter comp ound is prepared in situ from 5-chloroindole-2,3-dione and 4-fluoroani line. The structure of the title compound confirms the conclusions dra wn from the spectroscopic studies that the environment of the spiro C atom is based on tetrahedral geometry having bond angles in the range 109.6 (3)-117.3 (2)-degrees.