QUALITY-OF-LIFE AMONG PATIENTS POSTMYOCARDIAL INFARCTION AT BASE-LINEIN THE SURVIVAL AND VENTRICULAR ENLARGEMENT (SAVE) TRIAL

Citation
L. Gorkin et al., QUALITY-OF-LIFE AMONG PATIENTS POSTMYOCARDIAL INFARCTION AT BASE-LINEIN THE SURVIVAL AND VENTRICULAR ENLARGEMENT (SAVE) TRIAL, Quality of life research, 3(2), 1994, pp. 111-119
Citations number
30
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Public, Environmental & Occupation Heath",Nursing
Journal title
ISSN journal
0962-9343
Volume
3
Issue
2
Year of publication
1994
Pages
111 - 119
Database
ISI
SICI code
0962-9343(1994)3:2<111:QAPPIA>2.0.ZU;2-9
Abstract
A quality of life ancillary study was incorporated into the Survival a nd Ventricular Enlargement (SAVE) trial of captopril versus placebo am ong patients who survived an acute myocardial infarction with compromi sed ventricular functioning, but no overt heart failure. Assessments i ncluded patient symptoms, health perceptions, emotional, cognitive, so cial and sexual levels of functioning, as well as potential covariates , such as life events and social support. The purpose of this study wa s to evaluate the psychometric properties of the quality of life measu res in the SAVE at baseline, and provide a pre-randomization profile o f the SAVE patients. One hundred and eighty-four patients participated in this aspect of the trial. Reliability alpha coefficients were adeq uate or better for all questionnaires, except for life events and sexu al activities. Consistent with prior studies, the quality of life para meters were uncorrelated with ventricular ejection fraction. Despite e xperiencing a recent myocardial infarction with compromised ventricula r functioning, patients at baseline generally neither appeared depress ed nor focused on symptoms. The baseline findings support the inclusio n of the quality of life ancillary study in the overall SAVE trial bec ause of the independent contribution likely to be achieved in terms of evaluating both disease progression and treatment efficacy.