IS IT EASIER TO DIALYZE WOMEN THAN MEN

Citation
F. Maduell et al., IS IT EASIER TO DIALYZE WOMEN THAN MEN, Nephron, 67(2), 1994, pp. 146-149
Citations number
13
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Urology & Nephrology
Journal title
ISSN journal
0028-2766
Volume
67
Issue
2
Year of publication
1994
Pages
146 - 149
Database
ISI
SICI code
0028-2766(1994)67:2<146:IIETDW>2.0.ZU;2-W
Abstract
Since the urea kinetic model is used as an objective method for monito ring dialysis, it has been possible to shorten reasonably its duration . From the usual practice, we have observed that it is easier to reduc e the dialysis time in women as compared to men. The purpose of this s tudy is to find out the reason for such observation and to corroborate it. Fourty-two patients, 25 males and 17 females on 3-weekly dialysis (3 h/session) were studied. All patients were dialyzed under the same dialysis characteristics: 3-hour sessions, blood flow 350 ml/min, ult rafiltration 1.5 liters/h, 1.5-m(2) cuprophane membrane and bicarbonat e buffer. The dialysate was collected in a graduated tank. Urea concen tration in plasma and in the dialysate was measured. Then, the urea di stribution volume, dialyzer clearance, the KT/Vindex and protein catab olic rate were calculated. The KT/V value was higher in women with res pect to men, 1,017 +/- 0.10 versus 0.82 +/- 0.14 (p < 0.001). The urea distribution volume value was significantly higher in men as compared to women, 60.04 +/- 6.6 versus 51.48 +/- 5.88% (p < 0.001). There wer e no significant differences in dialyzer clearance, protein catabolic rate or body weight. In conclusion, under identical dialysis condition s, it is easier to dialyze women than men, because women's urea distri bution volume is lower than men's.