AMPLIFICATION OF HUMAN APO(A) KRINGLE 4-37 FROM BLOOD LYMPHOCYTE DNA

Citation
D. Pfaffinger et al., AMPLIFICATION OF HUMAN APO(A) KRINGLE 4-37 FROM BLOOD LYMPHOCYTE DNA, Biochimica et biophysica acta, 1225(1), 1993, pp. 107-109
Citations number
3
Language
INGLESE
art.tipo
Note
Categorie Soggetti
Biophysics,Biology
ISSN journal
0006-3002
Volume
1225
Issue
1
Year of publication
1993
Pages
107 - 109
Database
ISI
SICI code
0006-3002(1993)1225:1<107:AOHAK4>2.0.ZU;2-Q
Abstract
We have been able to amplify the lysine binding pocket region of human apo(a) kringle type 5 starting from the DNA isolated from peripheral blood lymphocytes. This development now permits the identification of Lp(a) mutants that by lacking their ability to bind to lysine/fibrin w ould have a lesser thrombogenic potential.