INVESTIGATION ON THE REACTIONS OF FLUORINATED 1,3-DIKETONES WITH 5-AMINOTETRAZOLE - SYNTHESIS OF SOME TETRAZOLO[1,5-A]-PYRIMIDINES AND BETA-KETOAMINE DERIVATIVES

Citation
Kc. Joshi et al., INVESTIGATION ON THE REACTIONS OF FLUORINATED 1,3-DIKETONES WITH 5-AMINOTETRAZOLE - SYNTHESIS OF SOME TETRAZOLO[1,5-A]-PYRIMIDINES AND BETA-KETOAMINE DERIVATIVES, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 32(8), 1993, pp. 886-888
Citations number
11
Language
INGLESE
art.tipo
Note
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
0376-4699
Volume
32
Issue
8
Year of publication
1993
Pages
886 - 888
Database
ISI
SICI code
0376-4699(1993)32:8<886:IOTROF>2.0.ZU;2-C
Abstract
Reactions of 5-aminotetrazole (II) with fluorinated 1,3-diketones (I(a -c)) in different media have been investigated and found to be solvent dependent. Tetrazolo[1,5-a]pyrimidines (III(a-c)) are exclusively obt ained in gl. acetic acid while beta-ketoamines (V(a-c)) of tetrezole a long with III(a-c) are obtained in abs. ethanol. The spectral data of the free schiff bases indicate that the site of amine condensation in unsymmetrical beta-ketoamines is the lesser enolized acyl oxygen and t he ketoamino-form is the predominant tautometer. The proposed structur es are fully corroborated by IR, PMR, F-19 NMR and mass spectral data.