STABLE CHROMOSOME-ABERRATIONS 25 YEARS AFTER SEVERE ACCIDENTAL RADIATION EXPOSURE

Citation
A. Maes et al., STABLE CHROMOSOME-ABERRATIONS 25 YEARS AFTER SEVERE ACCIDENTAL RADIATION EXPOSURE, Radiation and environmental biophysics, 32(4), 1993, pp. 319-324
Citations number
14
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Biophysics,"Radiology,Nuclear Medicine & Medical Imaging","Environmental Sciences
ISSN journal
0301-634X
Volume
32
Issue
4
Year of publication
1993
Pages
319 - 324
Database
ISI
SICI code
0301-634X(1993)32:4<319:SC2YAS>2.0.ZU;2-J
Abstract
A thorough cytogenetic analysis using G-banding was performed on 100 p eripheral blood lymphocytes from an individual who had been accidental ly exposed to radiation more than 25 years previously. More than 60% o f the analysed cells were found to possess one or more stable chromoso me aberrations (e.g. reciprocal translocations). Chromosomes 1 and 11 were more involved in these aberrations than would be expected from th e relative chromosome lengths. No identical stable aberrations were fo und, suggesting that, 25 years after near-lethal exposure, haemopoieti c stem cells display substantial diversity.