MOLECULAR-CLONING OF 2 NOVEL PROTEIN-KINASE GENES FROM ARABIDOPSIS-THALIANA

Citation
Tv. Moran et Jc. Walker, MOLECULAR-CLONING OF 2 NOVEL PROTEIN-KINASE GENES FROM ARABIDOPSIS-THALIANA, Biochimica et biophysica acta, 1216(1), 1993, pp. 9-14
Citations number
25
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Biophysics,Biology
ISSN journal
0006-3002
Volume
1216
Issue
1
Year of publication
1993
Pages
9 - 14
Database
ISI
SICI code
0006-3002(1993)1216:1<9:MO2NPG>2.0.ZU;2-O
Abstract
We have isolated two novel protein kinase genes, MHK and NAK, from the plant Arabidopsis thaliana by using low stringency hybridization with the catalytic domain of a putative plant receptor protein kinase. Seq uence analysis of the cDNAs reveals that MHK is a member of the cdc2family of protein kinases and is particularly similar to the mak gene of rats; mak encodes a protein kinase that may play a role in spermato genesis. NAK encodes a candidate protein kinase that is similar to the oncogenes met and abl. The homology that these two Arabidopsis genes share with other protein kinases suggests that they may play a role in the regulation of plant growth and development.