FUNCTION-TESTS ON THE NEUROENDOCRINE HYPOTHALAMOPITUITARY SYSTEM FOLLOWING ACUTE MIDBRAIN SYNDROME, WITH SPECIAL REFERENCE TO COMPUTERTOMOGRAPHICAL AND MAGNETIC-RESONANCE-IMAGING RESULTS
J. Lenzen et al., FUNCTION-TESTS ON THE NEUROENDOCRINE HYPOTHALAMOPITUITARY SYSTEM FOLLOWING ACUTE MIDBRAIN SYNDROME, WITH SPECIAL REFERENCE TO COMPUTERTOMOGRAPHICAL AND MAGNETIC-RESONANCE-IMAGING RESULTS, Neurosurgical review, 16(3), 1993, pp. 183-187
Seventeen patients underwent a neuroendocrinological function test at
a mean 6.3 years following a severe craniocerebral trauma (CCT) accomp
anied by midbrain syndrome. An insulin hypoglycaemia test (IHT) and th
e combined pituitary anterior lobe test (CPALT) were applied. Whereas
the IHT as maximum stimulator of the hypothalamo-pituitary system (HPS
) showed an adaequate reserve capacity, the CPALT yielded a partial li
mitation of the secretion dynamic in the somatotropic, adrenocorticotr
opic axis as well as a dysfunction in the FSH secretion. Neuroradiolog
ical tests could not establish substantial injury in the regio hypotha
lamica in any patient.