ACUTE ENCEPHALOPATHY AND POLYNEUROPATHY AFTER DISULFIRAM INTOXICATION

Citation
M. Zorzon et al., ACUTE ENCEPHALOPATHY AND POLYNEUROPATHY AFTER DISULFIRAM INTOXICATION, Alcohol and alcoholism, 30(5), 1995, pp. 629-631
Citations number
10
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Substance Abuse
Journal title
ISSN journal
0735-0414
Volume
30
Issue
5
Year of publication
1995
Pages
629 - 631
Database
ISI
SICI code
0735-0414(1995)30:5<629:AEAPAD>2.0.ZU;2-1
Abstract
A chronic alcoholic who had ingested a very high dose of disulfiram (2 9 g over a 1-week period) without simultaneous alcohol intake develope d an acute encephalopathy and a severe flaccid tetraparesis that worse ned over the course of several days, even after the intake of the drug had stopped. Recovery was both slow and incomplete. One year after in toxication, the patient still had distal weakness in the arms and legs , and hypestesia in the hands and feet.