2 CASES OF SEVERE BRONCHIECTASIS SUCCESSFULLY TREATED WITH A PROLONGED COURSE OF TRIMETHOPRIM SULFAMETHOXAZOLE/

Citation
T. Honda et al., 2 CASES OF SEVERE BRONCHIECTASIS SUCCESSFULLY TREATED WITH A PROLONGED COURSE OF TRIMETHOPRIM SULFAMETHOXAZOLE/, Internal medicine, 35(12), 1996, pp. 979-983
Citations number
15
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Medicine, General & Internal
Journal title
ISSN journal
0918-2918
Volume
35
Issue
12
Year of publication
1996
Pages
979 - 983
Database
ISI
SICI code
0918-2918(1996)35:12<979:2COSBS>2.0.ZU;2-D
Abstract
Two patients with severe bronchiectasis, one patient without other dis ease and the other with hyper IgE syndrome, were successfully treated with long-term therapy with low doses of trimethoprim and sulfamethoxa zole (TMP-SMZ), Recurrent respiratory infections with productive cough and high fever were resistant to various antibiotics and often distur bed the patients' activities in daily life, However, they showed marke d improvement following TMP-SMZ therapy, which was started for methici llin-resistant Staphylococcus aureus (MRSA) infection, MRSA disappeare d some months later, but Pseudomonas aeruginosa appeared again in the sputum, Both patients, however, have remained free from symptoms for o ver one year.