TC-99M HMPAO BRAIN SPECT COMPARED TO CT AND EEG AFTER SEIZURES IN CHILDHOOD

Citation
E. Alper et al., TC-99M HMPAO BRAIN SPECT COMPARED TO CT AND EEG AFTER SEIZURES IN CHILDHOOD, Clinical nuclear medicine, 20(9), 1995, pp. 803-806
Citations number
12
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
Journal title
ISSN journal
0363-9762
Volume
20
Issue
9
Year of publication
1995
Pages
803 - 806
Database
ISI
SICI code
0363-9762(1995)20:9<803:THBSCT>2.0.ZU;2-5
Abstract
Twenty-one children with various seizure disorders were studied using Tc-99m HMPAO brain SPECT, cranial CT, and electroencephalography (EEG) . The rates of pathologic findings on SPECT, CT, and EEG were 67%, 38% , and 52%, respectively, SPECT showed congruent, or more extensive, le sions in all eight patients with CT lesions. Six of the 13 children wh o had normal CT results, had abnormal SPECT study results, In this pos tictal series, 4 of the 14 abnormalities detected in the first SPECT s tudy that was applied within 24 hours of a seizure, were in the form o f hyperperfused areas. Eight of the 14 abnormal first SPECT studies ha d become normal by the second SPECT. We conclude that, with respect to the depiction of some kind of abnormality, HMPAO brain SPECT is super ior to CT and EEG, and considerable changes in brain perfusion are lik ely to occur over a period of a few weeks.